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TETRACYCLINE HYDROCHLORIDE

IUPAC Name: (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride

Symbol: TH

Molecular Formula: C22H24N2O8.HCl

Molecular weight: 480.9 g/mol

CAS No: 64-75-5

ATC Code: A01AB13   D06AA04   J01AA07

Drug Class: Antibacterial

General Properties:

Tetracycline Hydrochloride is the hydrochloride salt of tetracycline, a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis and bacterial cell growth. Because naturally fluorescing tetracycline binds to newly formed bone at the bone/osteoid interface, tetracycline-labeling of bone and fluorescence microscopy may be used to perform bone histomorphometry.

A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.

 

Indication:

Tetracycline is used to treat a wide variety of infections, including acne. It is an antibiotic that works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.Tetracycline can also be used in combination with anti-ulcer medications to treat certain types of stomach ulcers.

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