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MANNITOL INJECTION

IUPAC Name: (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol

Symbol: MI

Molecular Formula: C6H14O6

Molecular weight: 182.17 g/mol

CAS No: 69-65-8

General Properties:

Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure may be reduced. Mannitol may also be used for the promotion of diuresis before irreversible renal failure becomes established; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a renal function diagnostic aid.

.Indication:

Mannitol injection is used to lower pressure in the head (intracranial pressure) and increased pressure in the eye (intraocular pressure). It is also used to treat swelling of the brain (cerebral edema). This medicine is to be given only by or under the direct supervision of your doctor.

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