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IRBESARTAN

IUPAC Name: 2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one

Symbol: IR

Molecular Formula: C25H28N6O

Molecular weight: 428.5 g/mol

CAS No: 138402-11-6

Drug Class: angiotensin receptor blockers (ARBs)

General Properties:

Irbesartan is a biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. It has a role as an antihypertensive agent, an angiotensin receptor antagonist, an environmental contaminant and a xenobiotic. It is a biphenylyltetrazole and an azaspiro compound.

Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy. It can also be used as part of a combination product with [hydrochlorothiazide] for patients not well controlled or not expected to be well controlled on monotherapy. Unlike angiotensin converting enzyme inhibitors, ARBs are not associated with a dry cough. Irbesartan was granted FDA approval on 30 September 1997.

Irbesartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.

Indication:

Irbesartan is an angiotensin receptor blocker (ARB) medicine widely used to treat high blood pressure (hypertension). It relaxes and widens your blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body.

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