Molecular Formula: C24H44FeO25-
Molecular weight: 788.152102 g/mol
CAS No: 9007-72-1
Drug Class: Haematinic
General Properties:
Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex.
Ferric Carboxymaltose is a parenteral iron solution containing ferric iron complexed with carboxymaltose polymers, used in parenteral iron-replacement therapy. Upon administration, ferric carboxymaltose is removed from plasma by the reticuloendothelial system. Subsequently, ferric iron binds to transferrin or is stored as ferritin. Transferrin-bound iron is transported in the plasma to the liver, spleen and bone marrow, where it is incorporated into hemoglobin, and to muscle, where it is incorporated into myoglobin.
Indication:
Ferric carboxymaltose is an iron replacement product indicated for the treatment of iron deficiency anemia in patients ≥1 year of age who have an intolerance to, or unsatisfactory response from, oral iron therapy, and in adult patients who have non-dialysis-dependent chronic kidney disease. It is also indicated to treat iron deficiency and improve exercise capacity in adult patients with NYHA class II or III heart failure.