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NEOSTIGMINE METHYLSULFATE

IUPAC Name: [3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;methyl sulfate

Symbol: NM

Molecular Formula: C13H22N2O6S

Molecular weight: 334.39 g/mol

CAS No: 51-60-5

ATC Code: N07AA01

Drug Class: Anti-Cholinesterase

General Properties:

Neostigmine methyl sulfate is an arylammonium sulfate salt. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor.

A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.

 

Indication:

Neostigmine methylsulfate and glycopyrrolate combination injection is used to reverse the effects (eg, bradycardia and excess secretion) of non-depolarizing neuromuscular blocking agents (NMBA) after surgery. This medicine is to be given only by or under the supervision of your doctor.

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