Molecular Formula: C4H4FN3O
Molecular weight: 129.09 g/mol
CAS No: 2022-85-7
ATC Code: D01AE21
Drug Class: antimetabolite, antifungal
General Properties:
Flucytosine is an organofluorine compound that is
cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections. It has a role as a prodrug. It is an organofluorine compound, a pyrimidone, an aminopyrimidine, a nucleoside analogue and a pyrimidine antifungal drug. It is functionally related to a cytosine.
Flucytosine is an antifungal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of serious infections caused by certain strains of two types of fungi: Candida and Cryptococcus. For example, flucytosine is used to treat cryptococcosis, which is an infection caused by Cryptococcus fungi.
Cryptococcosis can be an opportunistic infection (OI) of HIV.
A fluorinated cytosine analog that is used as an antifungal agent.
Indication:
Flucytosine (5-fluorocytosine) is an FDA-approved medication indicated for the treatment of severe candida and cryptococcus infections. Administering care to patients prescribed flucytosine requires excellent interaction between the patient and an interprofessional team of healthcare providers.
